Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices

Mycobacteria Exploit Host Hyaluronan for Efficient Extracellular Replication

In spite of the importance of hyaluronan in host protection against infectious organisms in the alveolar spaces, its role in mycobacterial infection is unknown. In a previous study, we found that mycobacteria interact with hyaluronan on lung epithelial cells. Here, we have analyzed the role of hyaluronan after mycobacterial infection was established and found that pathogenic mycobacteria can gr...

On the spectra of some matrices derived from two quadratic matrices

begin{abstract} The relations between the spectrum of the matrix $Q+R$ and the spectra of the matrices $(gamma + delta)Q+(alpha + beta)R-QR-RQ$, $QR-RQ$, $alpha beta R-QRQ$, $alpha RQR-(QR)^{2}$, and $beta R-QR$ have been given on condition that the matrix $Q+R$ is diagonalizable, where $Q$, $R$ are ${alpha, beta}$-quadratic matrix and ${gamma, delta}$-quadratic matrix, respectively, of ord...

Hyaluronan Synthases from Streptococcus versus Pasteurella bacteria Hyaluronan Synthesis by Class I Hyaluronan Synthases Functional Sizes of the Hyaluronan Synthases Purification and Characterization of the Streptococcal Hyaluronan Synthases The Phospholipid Requirement of the Streptococcal Hyaluronan Synthases

Action pattern and substrate specificity of the hyaluronan lyase from group B streptococci.

The hyaluronan lyase of group B streptococci rapidly cleaves hyaluronan by an elimination mechanism to yield the unsaturated disaccharide 2-acetamido-2-deoxy-3-O-(beta-D-gluco-4-enepyranosyluronic acid)-D-glucose. Additionally, it has been shown that the enzyme has limited specificity for achondroitin sulphate and cleaves the chain at unsulphated sites [Baker,Yu, Morrison, Averett and Pritchard...

Modulation of growth in retina-derived cells by extracellular matrices.

Intravitreal membranes from patients with proliferative vitreoretinopathy (PVR) consist partly of retinal glial (RG) and retinal pigment epithelial (RPE) cells surrounded by varying amounts of extracellular matrix (ECM). The contribution of the ECM to the growth of PVR membranes is unknown. This study was undertaken to determine if proliferation in cultured RPE and RG cells is affected by diffe...